Starbrands Ltd, a leading UK manufacturer
of cleaning products, wanted to confirm that their non-biological
detergent products were kept free from the enzyme additives used in
their biological products during the production process.
Enzymes are added to biological cleaning products in small
quantities to improve their cleaning action and stain removal
properties. Some enzymes (proteases) can cause dermatitis;
proteases, lipases and amylases are widely found in cleaning
products. Although safe when used correctly, some consumers
choose not to use biological products.
Starbrands also needed results from submitted samples on a
timescale that did not interfere with production deadlines. This
involved us modifying our normal sample turnaround time and
maintaining a close working relationship.
Detergents in a concentrated form tend to be aggressive chemical
mixtures, often with high alkaline pHs, and would normally be
unsuitable for measurement by an immunoassay. However, our team is
experienced in developing allergen methods appropriate for the very
low levels found in air samples; by diluting out the detergent's
potential deleterious effects, they soon had an assay capable of
detecting the protease at the low ppb levels in concentrated
detergent, achieving a sensitivity of around 10ppb.
Starbrands Ltd have been able to demonstrate that their
non-biological products are essentially free of this particular
protease, giving confidence in their production methods and quality
We are looking at the possibility of undertaking similar
monitoring for another enzyme (amylase) that the customer uses in
some of their biological products to remove starchy stains such as
gravy and sauces.
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to discuss how we could apply our skills in high sensitivity
immunoassays to support your product quality control
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